Evaluation of CTP - creatinine for predicting prognosis of cirrhosis patients with acute variceal bleeding

Abstract

Background: Variceal bleeding is a severe complicaton of portal hypertension due to cirrhosis with high rate of motality. This study to evaluate the accuracy CTP - Creatinine score for predicting early rebleeding and mortality and in first 6 weeks in cirrhosis patient with acute variceal bleeding. Methods: Prospective study in 118 cirrhosis patients presenting with acute variceal bleeding were hospitalized and diagnosed by upper GI endoscopy. Exclusion criteria were patients with chronic kidney diseases. Results: The mean values of the CTP - Crea I and CTP - Crea II score are 9.03 ± 2.73 and 8.97 ± 2.65, respectively. The CTP - Crea I score was valuable in predicting outcomes early rebleeding with AUC = 0.788, early death with AUC = 0.860 and within the first 6 weeks: rebleeding with AUC = 0.672 and mortality AUC = 0.818. The CTP - Crea II score has predictive value for outcomes early rebleeding with AUC = 0.771, early death with AUC = 0.859 and mortality within the first 6 weeks with AUC = 0.805. Conclusions: CTP - Creatinine scores have good value in predicting outcome in cirrhosis patients with acute variceal bleeding. Can be applied to evaluate and stratify those cirrhosis patients in clinical practice in Vietnam. Key words: variceal bleeding, CTP, Creatinine.