Evaluation of clinical and non-clinical parameters among partial and total mastectomy patients

Abstract

BackgroundMastectomy is a common surgical procedure performed on the breast cancer patients. A number of factors influence the choice regarding the type of mastectomy and postoperative outcomes including survival rate. ObjectiveThe aim of this study is to compare clinical and nonclinical parameters among partial (breast conserving surgery) and total mastectomy patients referred to our center. MethodIn this retrospective study, 279 women who underwent partial or total mastectomy were included. A questionnaire comprising of demographic data such as; age, marital status, employment status, education level and smoking, clinical data such as; grade of tumor, tumor side, breast reconstruction (prosthesis status), biopsy status, involvement of lymph node and postoperative stress and data regarding comorbidities was drafted for all the patients. ResultOverall, 78 and 201 underwent total and partial mastectomy, respectively. Patients who underwent partial mastectomy were significantly younger p < 0.001, underwent radiation and chemotherapy p < 0.001 and p = 0.018, respectively, had significantly greater incidence of heart disease p = 0.012 and were presented with greater postoperative stress p < 0.001. Patients who received total mastectomy were more to receive breast reconstruction (prosthesis) p = 0.035 and had greater lymph node involvement. The grade and side of tumor, employment status, diabetes, smoking, thyroid disease and type of incision was not significant among the two groups. ConclusionOur study concludes that a number of clinical and nonclinical parameters can affect the decision of the type of mastectomy among the patients. Studies regarding postoperative outcomes such as recurrence and mortality need to be added to this data.