Abstract
Severe sepsis and septic shock are common and frequently fatal problem in I.C.U. Recent therapeutic advances to routine clinical practice has proven controversial, because of their pleiotropic effects related to many pathophysiological determinants of sepsis. Statin therapy could be the next step in the search for adjuvant therapy. This study was done to evaluate chronic statin therapy on outcome of patients with sepsis and septic shock in I.C.U
Highlights
Severe sepsis and septic shock are common and frequently fatal problem in I.C.U
The primary end point was the number of organ failure free days, hemodynamic failure free days and organ dysfunction free days up to day 14
Chronic statin therapy in I.C.U septic patients was associated with reduction in the severity of organ failure and Submit your manuscript to a journal and benefit from: Submit your manuscript at 7 springeropen.com
Summary
Severe sepsis and septic shock are common and frequently fatal problem in I.C.U. Recent therapeutic advances to routine clinical practice has proven controversial, because of their pleiotropic effects related to many pathophysiological determinants of sepsis. Methods We compared patients with severe sepsis and septic shock.
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