Evaluation of Choroidal and Retinal Thickness Changes in Parkinson’s Disease Using Spectral Domain Optical Coherence Tomography

Abstract

ABSTRACTPurpose: The purpose of this study was to evaluate retinal and choroidal thickness in patients with Parkinson’s disease (PD) using spectral domain-optical coherence tomography (SD-OCT). Material and methods: Participants in our study were 31 PD patients and 25 age-matched healthy controls. All participants underwent best-corrected visual acuity (BCVA) measurement, slit-lamp biomicroscopy, dilated fundoscopy, and SD-OCT. Macular and retinal nerve fiber layer (RNFL) thickness and choroidal thickness in all quadrants were recorded. Results: There was a statistically significant reduction in average, superior, and temporal RNFL thickness, average ganglion cell complex, and choroidal thickness in the subfoveal area and in all quadrants between patients with PD and controls. Conclusions: The role of the choroidal vasculature in the pathophysiology of PD should be further scrutinized.