Abstract
Fast cine phase contrast magnetic resonance angiography (PC-MRA) has the potential to provide a quantitative measurement method for the diagnosis and treatment of cerebrovascular disease. To evaluation the changes of cerebral blood flow and the characteristics of artery lesion distribution in the patients of transient ischemic attacks (TIA). In all, 98 normal subjects and 106 TIA patients who underwent MRI examination within 72 h after the last symptom onset including the DWI sequence to exclude acute cerebral infarction were enrolled. The blood flow of the cranial total, the area of the internal carotid artery and vertebral artery, the average velocity, and the average blood flow were obtained and compared in normal subjects and TIA group. Analysis of Variance (ANOVA), t-test, and Kruskal-Wallis test were used for statistical assessments. The total cerebral blood flow of the TIA group and normal control group was no significant statistical difference (P > 0.05). The total blood flow decreased with increasing age, and the TIA group was much lower than the control group. The blood flow of the right internal carotid artery in the TIA group had a significant difference compared with controls (P < 0.05). However, the same situation did not happen in both of the left internal carotid artery and vertebral artery. Phase contrast magnetic resonance imaging has the potential to evaluate the change of cerebral blood flow in TIA patients. The decrease in the total blood flow and the symptom onset of TIA is consistent. Phase contrast magnetic resonance imaging could provide guidance to the diagnosis of TIA.
Highlights
Transient ischemic attacks (TIA) represent a frequent neurovascular condition associated with a risk of stroke recurrence of 5% at 48 h and 10% at 3 months in the absence of specific management [1]
The results showed that there was no significant difference in the whole cerebral blood flow between the TIA group and the normal control group (P > 0:05)
The risk of ischemic stroke in these TIA patients increased with some risk factors such as the degree, extent, or duration of vascular stenosis
Summary
Transient ischemic attacks (TIA) represent a frequent neurovascular condition associated with a risk of stroke recurrence of 5% at 48 h and 10% at 3 months in the absence of specific management [1]. The phase displacement of the flowing protons is generated by the accumulation of two different positive and negative gradients between the two gradients, and this phase displacement is proportional to the movement of the flowing protons in the direction of the flow code. We subtract these two images, and we get an image of just the protons flowing. This phase change is the key of phase-sensitive flow imaging technology [9]
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