EVALUATION OF CENTRAL HEMODYNAMICS USING THE RADIAL ARTERIAL PULSE WAVE IN CHILDREN AND YOUNG ADULTS

Abstract

Objective: Evaluation of central hemodynamics is useful in prevention and treatment of cardiovascular diseases. In this study, we examined the accuracy of non-invasively measured central hemodynamics in children and young adults. Design and method: This study enrolled 19 patients who had undergone a cardiac catheterization below 28 years old (9.7 ± 7.3 years). Ascending aortic blood pressure was measured recorded using a pressure sensor-mounted catheter (model SPC-454D, Millar Instrument, Inc., Houston, Texas). Radial artery pulse waves were simultaneously measured non-invasively by tonometry (HEM-9000AI, Omron Healthcare Co., Ltd., Kyoto, Japan). We analyzed the degree of coincidence between ascending aortic systolic blood pressure (aSBP) and estimated central systolic blood pressure by tonometry (estCBP) using 36 simultaneous recording of aSBP and estCBP. We also analyzed the relationship between aortic augmentation index (aAI) and radial augmentation index (rAI). Results: The aSBP was 95.5 ± 13.1 mmHg and estCBP was 88.5 ± 19.9mmHg. There was a significant relationship between aBP and estCBP (aSBP = 0.78 (estCBP) + 22.7, r = 0.82, p < 0.01). The mean difference of the aSBP minus eCBP was 2.6 ± 8.0 mmHg by Bland-Altman analysis. The rAI was 64.0 ± 15.1% and aAI was 14.9 ± 10.0%. There was a significant correlation between two parameters (r = 0.40, p = 0.015). Conclusions: The estimation of central hemodynamics by the radial artery tonometry is useful for children and young adults.