Abstract
Purpose: The prevalence of atopy has been investigated in different autoimmune diseases in various studies. But, the atopic status in primary Sjögren’s syndrome (pSS) patients has not been evaluated yet. We aimed to determine the relationship between pSS and atopy. 
 Material and Method: Fifty consecutive adult patients with pSS and fifty age and sex-matched controls were prospectively recruited in this study pSS patients were evaluated with laboratory tests and disease activity score. All subjects underwent skin prick test to a standard panel of common aeroallergens.
 Results: Ten patients (10/50, 20%) in the pSS group and five patients (6/50, 12%) in the control group had positivity on skin prick tests with common inhalant allergens (p=0.267). No significant differences were found regarding the clinical characteristics between atopic and non-atopic pSS patients.
 Conclusions: Atopic status and allergen sensitization were evaluated in pSS patients. To our knowledge, this is the first study investigating the inhalen allergen spectrum in pSS patients. The prevalence of atopy is similar in patients with pSS to the controls. But atopy may be related to milder clinical manifestations of pSS.
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