Abstract
Hepatoprotective activity of Parmelia perlata (Huds.) Ach. against CCl4 induced liver toxicity in Albino Wistar ratsSunita Shailajan, Mayuresh Joshi, Bhavesh Tiwari
Highlights
Urolithiasis or nephrolithiasis, presence of calculi in kidney or any part of urinary tract, is the third most prevalent renal disease that afflicting humankind since antiquity
This manuscript was aimed to evaluate the antiurolithiatic potential of Parmelia perlata extract (PPE) against calcium oxalate calculi in experimental rats
The experimental findings showed that PPE exhibited significant antiurolithiatic potential against calcium oxalate calculi in experimental rats
Summary
Urolithiasis or nephrolithiasis, presence of calculi in kidney or any part of urinary tract, is the third most prevalent renal disease that afflicting humankind since antiquity. Goyal et al / Journal of Applied Pharmaceutical Science 8 (01); 2018: 129-135 used as the ingredient in some composite herbal formulations prescribed for urolithiasis patients, but, rationale behind their use has not been scientifically substantiated using modern methodology One such herbal lichen Parmelia perlata was identified and focussed in this manuscript. P. perlata (Huds.) Ach., belonging to family Parmeliaceae, is commonly known as Chharila, Some other common names like Stone flower, Pattharphool, etc., given to this are probably because of its traditional therapeutic uses in urinary calculi (Goyal et al, 2016) It contains several phytoconstituents including lichen acids like lecanoric acid, atranorin, usnic acid (Khare, 2007; The Ayurvedic Pharmacopoeia of India, 2001), dibenzofuran (Sharma et al, 2014), terpenes (Abdullah et al, 2007), phenolic compounds, etc. The present manuscript is focussed to evaluate the hydroethanolic extract of P. paelata for antiurolithiatic potential against CaOx calculi in experimental rats
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