Abstract
Inflammation of the lining of the stomach is one of the most prevalent health problems that people face. In this study, the effects of herbal medication on the digestive system were examined in relation to the use of the cold-water immersion technique. Material & Methods: Male albino 6-week-old albino rats weighing 200-250 g each were used in the investigation. For three months, the animals were housed in the animal facility of the NIET Pharmacy Institute at 20°C (3°C) and 50-60% relative humidity. Researchers discovered non-lethal cold-water immersion in a small sample of six rats that caused stomach ulcers. After an 18-hour fasting, rats were immersed in ice-cold water. Researchers were able to examine the mucosa by isolating the stomach of rats. Result: In a model of cold-water immersion, honey has a unique effect on ulcer severity. esomeprazole is a medication used to treat acid reflux. According to phytochemical screening, the presence of flavonoids, triterpenes, and the anti-oxidant capacity of the crude drug mixture enhances antioxidant status and promotes mucus production. These elements may be responsible for the protective effect on stomach ulcer treatment. Conclusion: The content of flavonoids and triterpenes of honey and cinnamon powder mixture should be analyzed.
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