Evaluation of anti-ulcer and analgesic activity of Annona squamosa leaves

Abstract

In the present research work, medicinally important dried leaves of Annona squamosa were demonstrated for the identification of phytochemical compounds and Pharmacological activities. Plants were very important in medicinal field; they have similar properties as conventional drugs. Medicinal plants are safer due to their lower chances of adverse effects and better compatibility to human being. Different solvents are used to extract the biological compounds present in the leaves; among them methanol shows more biological compounds. Chemical constituents derived from plant source have a very long history in treatment of human diseases. Nearly 70% of new chemical entities reported during the past decades were from natural products. In the present study, on abdominal section histopathological observation for analgesic and antiulcer activities were reported. Analgesic activity was observed to the level of clinical importance, this activity was due to the presence of flavonoids and antiulcer activity exhibited due to mucosal defensive factor, than can be used for treatment of peptic ulcer. Further research is required to identify the active phytoconstituents present in the extract and experimentation on the healing action of drug as well as less side effects. The present investigation on mode of action may give way for establishment of new anti-ulcer and analgesic activity.