Abstract
Plants are the natural source of antioxidants as well as antimicrobial compounds that has great potentials in pharmaceutical industry. In the present study, two medicinal plants Atropa belladonna and Matricaria chamomilla were collected from Northern areas of Pakistan. The extracts of the collected plants were obtained by microwave assisted extraction (MAE) with changing parameters, power level and time; methanol and ethanol were solvents used during extraction. The extracts of plants were tested against different bacterial strains. It was observed that ethanolic extracts of Atropa belladonna has more significant antimicrobial activity against S.aureus than E.coli. In parallel, methanolic extract of Matricaria chamomilla showed greater significant antibacterial activity against S.aureus when compared with E.coli. In comparison, ethanolic extracts of Matricaria chamomilla has shown more significant results against S. aureus than E.coli (p ≤ 0.05). Both plants had no antibacterial activity against S.typhi. The free radical scavenging activity observed by DPPH assay, indicate that both plants have antioxidant activity at all levels of concentrations in solvent tested during the present work. However, methanolic extracts had greater antioxidant activity when compared with ethanolic extracts. Present study is thus helpful in highlighting present potentials for antioxidant and antimicrobial properties in the selected plants.
Highlights
The extracts of medicinal plants are used directly or indirectly for the treatment of many diseases
It has been well-known for many years that plant extracts and essential oil have antioxidant and antimicrobial effects
Two medicinal plants Matricaria and Atropa were tested against ATCC bacterial cultures Staphylococcus aureus, Escherchia coli and Salmonella typhi to determine and investigate their antibacterial potentials
Summary
Plants are the natural source of antioxidants as well as antimicrobial compounds that has great potentials in pharmaceutical industry. Two medicinal plants Atropa belladonna and Matricaria chamomilla were collected from Northern areas of Pakistan. Results: It was observed that ethanolic extracts of Atropa belladonna has more significant antimicrobial activity against S.aureus than E.coli. Methanolic extract of Matricaria chamomilla showed greater significant antibacterial activity against S.aureus when compared with E.coli. Ethanolic extracts of Matricaria chamomilla has shown more significant results against S. aureus than E.coli (p≤0.05). Both plants had no antibacterial activity against S.typhi. The free radical scavenging activity observed by DPPH assay, indicate that both plants have antioxidant activity at all levels of concentrations in solvent tested during the present work. Conclusion: Present study is helpful in highlighting present potentials for antioxidant and antimicrobial properties in the selected plants
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