Abstract

The present study aimed at evaluating the in vitro study of antioxidant activity of crude extracts (methanol, acetone, ethyl acetate and chloroform) of stem and leaves of physalis minima. The antioxidant activity was determined by two methods DPPH (1, 1-diphenyl- 2-picryl hydroxyl) assay and reducing power assay. The DPPH free radical scavenging activity of stem and leaves of physalis minima was determined at different concentration (200 µg, 400 µg, 600 µg and 800 µg). The entire tested sample showed lower scavenging activity than standard. The scavenging effect and reducing power of the eight extracts of the leaf and stem decreased in order of Methanol leaf extract > Methanol stem extract > Acetone leaf extract > Ethyl acetate leaf extract > Acetone stem extract > Ethyl acetate stem extract > Chloroform leaf extract > Chloroform stem extract. Thus result clearly indicated that the methanolic extract of leaf of P.minima showed higher activity compared to other extracts of stem and leaves. Hence is effective in scavenging free radical and has the potential to be a powerful antioxidant.

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