Abstract
24Jul 2017 EVALUATION OF ANTINEPHROLITHIC ACTIVITY OF BENINCASA HISPIDA (THUNB) COGN. IN WISTAR ALBINO RATS AGAINST ETHYLENE GLYCOL INDUCED NEPHROLITHIASIS. Qadrie ZL , Humaira A and Anandan R. Professor and Head, Department of Pharmacology and Toxicology, Pratishta Institute of Pharmaceutical Sciences, Durajpally, Hyderabad, Telangana. Ph.D. Scholar, Dept of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry, Sher I Kashmir University of Agricultural Sciences & Technology-Kashmir, Srinagar, J&K. Professor and Head, Department of Pharmacology & Toxicology, Vinayaka Mission?s College of Pharmacy, Salem, Tamil Nadu.
Highlights
ESBH at dose levels of 250 and 500 mg/kg body weight showed marked recovery in weight loss when compared to Ethylene glycol (EG) treated group
The urine volume, urine were decreased as well as oxalates, calcium, phosphorus, sodium and potassium excretion in urine, serum urea, uric acid, creatinine and blood urea nitrogen (BUN) contents were increased in lithiatic group as compared to normal control group
The results demonstrate that the ethanolic and aqueous extracts of Benincasa hispida seeds have potent anti-nephrolithiatic activity against nephrolithiasis induced by ethylene glycol in wistar albino rats
Summary
EVALUATION OF ANTINEPHROLITHIC ACTIVITY OF BENINCASA HISPIDA (THUNB) COGN. IN WISTAR ALBINO RATS AGAINST ETHYLENE GLYCOL INDUCED NEPHROLITHIASIS. 1. Professor and Head, Department of Pharmacology and Toxicology, Pratishta Institute of Pharmaceutical. 2. Ph.D. Scholar, Dept of Animal Nutrition, Faculty of Veterinary Sciences and Animal Husbandry, Sher I. Kashmir University of Agricultural Sciences & Technology-Kashmir, Srinagar, J&K. 3. Professor and Head, Department of Pharmacology & Toxicology, Vinayaka Mission’s College of Pharmacy, Salem, Tamil Nadu
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