Abstract
The methanolic extract along with some organic soluble fractions of the bark of Dillenia indica Linn. were tested against four Gram-positive and seven Gram-negative bacteria and against three pathogenic fungi. N-Hexane and dichloromethane fractions showed remarkable activities against all the tested bacteria but n-Hexane fraction showed highest activity against Shigella dysenteriae and its zone of inhibition was 15.51 ± 0.75 mm. Other showed moderate or little activity. Methanol crude extract showed highest activity against fungus Candida albicans with a zone of inhibition 13.13 ± 1.75 mm. Lowest minimum inhibitory concentration (MIC) values were observed in n-Hexane fraction against Shigella dysenteriae and Staphylococcus aureus and were 0.312 in both cases. Lowest LC 50 value 19.02 ± 1.16 of n-Hexane fraction indicated the highest toxicity incomparison with the other fractions.
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