Abstract
Background: Medicinal plants contain components of therapeutic value and provide an alternative form of available antibiotics to multiple infections. Development of microbial resistance to the available antibiotics has further enhanced the investigation of the role of antimicrobial activity of medicinal plants. Method: Here we report the antimicrobial properties of Artemisia afra, Psidium guajava and Erythrina lysistemon extracts obtained by using two different extraction solvents. Extracts were subjected to tests using zones of inhibition, Thin Layer Chromatography and High Pressure Liquid Chromatography (HPLC). Results: Pronounced antimicrobial activity was observed against Staphylococcus aureus using the ethanol extraction technique. However, no statistical significance was observed between the results produced using extracts from both methods A (according to dilution factor) and B (method 3a of the German Homeopathic Pharmacopoeia). Conclusion: The potential for developing antimicrobials from plants in vivo provides a platform for phytomedicine and pharmacological studies.
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