Abstract
Objective: The enriched Boswellia extract (Olibose®) and Regular Boswellic acid extract (RBAE) prepared from the resin of Boswellia serrata were evaluated for anti-inflammatory activity in Human Dermal Fibroblasts (HDF) Cells In-vitro. Methodolgy: Anti-inflammatory activity was determined by inducing inflammation on HDF and L929 cell lines. After the induction of inflammation, cells were treated with Olibose®, RBAE extracts and standard inflammatory drug Dexamethasone. Levels of Inflammatory markers i.e., TNF-α and NO (Nitric oxide) were measured and anti-inflammatory efficacy was assessed. Results: Results of the present study revealed that, the enriched extract (Olibose®) possess better anti-inflammatory activity in comparison with RBAE. Conclusion: In this study, Olibose® exhibited dose dependant anti-inflammatory activity against LPS induced induction of TNF-α and NO in HDF cells. Olibose® was found to have better anti-inflammatory activity than RBAE in vitro. Since arthiritis/ osteoarthiritis are associated with inflammation, this study proves that Olibose® can be used to reduce above said complications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: American Journal of Phytomedicine and Clinical Therapeutics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
