Abstract
Evaluation of Antibacterial Effect of Cucurbita pepo (Yakten) Extracts on Multi-antibiotic Resistance Bacterial Strains Isolated From Human Urinary Tract Infections
Highlights
The current study investigated that the antimicrobial components of three parts of Cucurbita pepo are cortex, core and whole fruit against multi-antibiotic resistance strains (Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, and Proteus mirabilis) which were isolated biochemically from human urinary tract infections
The results revealed that alcoholic and aqueus cortex extract of Cucurbita pepo gave high effect on Staphylococcus aureus
Using core fruit extraction (Aqex or Alcoholic extract (Aex)) the results showed no effect on any pathogenic bacteria
Summary
The numbers of pathogenic multiresistant bacterial strains that carry resistance to many antibiotics were increased gradually. The most important antibiotic sources is the plants which provide us with different antimicrobial agents. It was investigated that Cucurbita pepo has phenolic contents with antioxidant capacity (Leman et al, 2007). This plant contains carotenoids which used as provitamin A carotenoids, for human health, that is, reduction of the risk of degenerative diseases such as cancer, cardiovascular diseases, cataracts (Godoy and Rodriguez, 1998). The current study investigated that the antimicrobial components of three parts of Cucurbita pepo are cortex, core and whole fruit against multi-antibiotic resistance strains (Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, and Proteus mirabilis) which were isolated biochemically from human urinary tract infections
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