Abstract
Dental caries, which has a complex etiology brought on by several facultative anaerobes, is a well-known serious oral health issue in the majority of developing countries. The primary pathogen linked to this illness is Streptococcus mutans. S. mutans species that are resistant to numerous commercial antibiotics have been found in dental caries patients. Multi-drug resistance (MDR) is a natural occurrence that poses a significant global hazard to human health. While there are several therapeutic options for treating or preventing dental decay, the worldwide burden of MDR-related diseases is continually growing. In order to evaluate the effectiveness of different Moringa oleifera leaf extract as a solvent to control S. mutans infection the current study was created. S. mutans was isolated and identified, then used the disc diffusion method to assess the isolates' susceptibility to antibiotics as well as different extracts. The results of a one-way ANOVA exposed significant (P< 0.001) differences between the various extract solutions and S. mutans. The highest level of efficacy among the three extract was ethanol extract on another hands the cold distal water extract was the lowest efficacy against S. mutans. M. oleifera solution with ethanol extract is more effective than the other extract types.
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