Abstract
Drynaria qu ercifolia is a plant having wide spread ethno pharmacological uses. The aim of this study was to evaluate the anti - oxidant, anti - microbial and cyto toxic activities of the whole plant Drynaria quercifolia . The rhizome of the plant was sun dried and extract ed using methanol. Later the crude methanolic extract was fractionated into four different fractions using Petrole um ether, carbon - tetrachloride, Ethyl acetate and water . The anti - oxidant activity of the different fractions was measured by the DPPH free ra dical scavenging activity. The ethyl acetate , carbon - tetrachloride and showed very potent anti - oxidant activity by the DPPH free radical scavenging method. The anti - microbial activity of the different fractions was measured by disc diffusion method using c iprofloxacin as a standard. In vitro antimicrobial screening of the plant showed that ethyl acetate and the carbon tetra chloride fractions showed mild anti microbial activity. Evaluation of cyto - toxic activity was done using the brine - shrimp lethality bio - assay. The petroleum ether soluble fraction showed significant cyto - toxic potential with LC 50 values of 5.59 µg / ml.
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