Abstract
The present study was envisaged to assess the rationality for the use of traditionally in vogue herb Atropa acuminata as an anti-inflammatory agent. The drug, that is, A. acuminata when tested against carrageenan induced paw oedema showed significant anti-inflammatory activity at the dose of 1 g/kg body weight. The effects were analyzed by following the evaluation of various biochemical parameters including succinate dehydrogenase (SDH), gamma-glutamyl transpeptidase (GGT), lipid peroxidation (LPO), nitric oxide (NO), superoxide dismutase (SOD), glutathione, xanthine oxidase (XO), catalase and reduced glutathione peroxidase (GPx) were measured and the results suggested that the extracts possess significant anti-inflammatory activity, and with regard to certain parameters, the extracts performed fairly well than the allopathic drug, Diclofenac. Key words: Atropa acuminate, anti-inflammatory lipid peroxidation activity, carrageenan
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
