EVALUATION OF ANALGESIC ACTIVITY OF SHOREA ROBUSTA RESINS

Abstract

Shorea robusta (Sal), an important traditional Indian medicinal plant used in various ailments and rituals and the indigenous use of the resin of this plant as a medicament for treatment of various inflammatory conditions is well documented in literature. In the present study, ethanolic extract of S. robusta resin (SRE) was evaluated for its analgesic activity by making use of different central and peripheral pain models. The phytochemical studies have shown the presence of many secondary metabolites belonging to terpenoids, flavonoids, carbohydrate, lignans, phenols and sterols. Crude extracts and isolated compounds from Shorea robusta show a wide spectrum of pharmacological activities, such as anti-inflammatory, anti- obesity, antibacterial, wound healing, anti-pyretic & analgesic activities. Many studies have provided evidence for various traditional uses. The present review on its botany, traditional uses, pharmacological activities and phytochemistry which provides preliminary information for further studies for this potential medicinal plant. Pain is an unpleasant sensation and emotional experience linked to tissue damage. Pain occurs when something hurts, causing an unpleasant or uncomfortable feeling. The nearness of pain implies that something isn't right. Each individual is the best judge own pain. Pain of any origin comprises an individual’s life. The analgesic activity of SRE was assessed by employing different Materials and Methods: pain models such as, i) hot plate and tail flick tests for central analgesia.