Abstract
Evaluation of Addition Of Sildenafil Citrate On Fetal Growth And Doppler Indices In Treatment of Pregnancy Induced Hypertension
Highlights
Pregnancy induced hypertension (PIH) is the most common complication during pregnancy and it affects up to 12% of pregnancies
Using two groups with 30 patients in each group as follows: 1. Study group (Sildenafil group): We offered Sildenafil citrate (20 mg orally three times daily until delivery) as innovative therapy to 30 women with PIH in addition to antihypertensive drugs and other drugs like MgSO4, Omega-3. 2.Placebo group: We offered placebo which is a vitamin the same in shape and texture in addition to antihypertensive drugs and other drugs like MgSO4, Omega-3 to 30 women with PIH
Using two groups with 30 patients in each group as follows: Study group (Sildenafil group): We offered Sildenafil citrate (20 mg orally three times daily until delivery) as innovative therapy to 30 women with PIH in addition to antihypertensive drugs and other drugs like MgSO4, Omega-3
Summary
Pregnancy induced hypertension (PIH) is the most common complication during pregnancy and it affects up to 12% of pregnancies. It is the leading cause of maternal and fetal morbidity and mortality (1). The International Society for the Study of Hypertension in Pregnancy (ISSHP) classifies hypertension in pregnancy as follows: chronic hypertension, gestational hypertension, preeclampsia- de novo or superimposed on chronic hypertension, or white coat hypertension (10). It has many fetal and maternal complications. It is desirable to know the accurate changes in utero-placental and fetal circulation to predict perinatal outcome and help in appropriate intervention (6)
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