Evaluation of Accuracy and Performance of isCGM Sensors during Experimentally Induced Glucose Excursions. Comment on Moser et al. Performance of the Intermittently Scanned Continuous Glucose Monitoring (isCGM) System during a High Oral Glucose Challenge in Adults with Type 1 Diabetes-A Prospective Secondary Outcome Analysis. Biosensors 2021, 11, 22.

Wiebke Jessen,Alexander Seibold

doi:10.3390/bios12030152

Abstract

A 2021 publication in Biosensors from Moser and colleagues [...].

Highlights

A 2021 publication in Biosensors from Moser and colleagues [1] reported on the accuracy of the FreeStyle Libre® intermittently scanned continuous glucose monitoring system at different rates of change in plasma glucose (RCPG), during two oral glucose tolerance tests (OGTT) in 19 adults with type 1 diabetes (T1D), following 12 and 36 h fasting periods
They concluded that the FreeStyle Libre system is accurate when compared to reference plasma glucose during OGTT glycemic challenge, but that its performance was dependent on the RCPG and that it overestimated glucose during periods when reference blood glucose values were in hypoglycemia
The most recent algorithm for the FreeStyle Libre sensor does not report the mean absolute relative difference (MARD) for readings exclusively

Summary

Introduction

A 2021 publication in Biosensors from Moser and colleagues [1] reported on the accuracy of the FreeStyle Libre® intermittently scanned continuous glucose monitoring (isCGM) system at different rates of change in plasma glucose (RCPG), during two oral glucose tolerance tests (OGTT) in 19 adults with type 1 diabetes (T1D), following 12 and 36 h fasting periods. They concluded that the FreeStyle Libre system is accurate when compared to reference plasma glucose during OGTT glycemic challenge, but that its performance was dependent on the RCPG and that it overestimated glucose during periods when reference blood glucose values were in hypoglycemia.

Results

Conclusion