Abstract
A serum extender, SERASUP II, was evaluated for its ability to maintain VERO cell cultures at long term, and for its influence on virus production by cells adapted to that medium. SERASUP II allowed a 90% reduction of the serum amount while maintaining a correct long-term growth. The production of Poliovirus strains 1 and 2 is improved in the extender containing medium, while it is strongly decreased for strain 3.
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