Evaluation of a new semi-automatic strategy for quantitative measurement of infarct size in patients with acute and chronic myocardial infarction using cardiac magnetic resonance imaging

Gunnar Lund,Karsten Sydow,Dennis Saering,Peter Bannas,Kai Muellerleile,Dominik Barz,Julia Cuerlis,Ulf K Radunski,Gerhard Adam

doi:10.1186/1532-429x-15-s1-p201

Abstract

Background Cardiac magnetic resonance imaging (CMR) with delayed gadolinium enhancement (DE) enables accurate infarct size measurement, however, the evaluation of infarct size using a threshold method is time consuming and relies on accurate placement of normal regions of interest and manual delineation of the infarct size. The purpose of the study was to analyze the accuracy and expenditure of time of a new evaluation strategy for infarct size measurement using delayed enhancement CMR in comparison to a standard evaluation.

Highlights

Cardiac magnetic resonance imaging (CMR) with delayed gadolinium enhancement (DE) enables accurate infarct size measurement, the evaluation of infarct size using a threshold method is time consuming and relies on accurate placement of normal regions of interest and manual delineation of the infarct size.The purpose of the study was to analyze the accuracy and expenditure of time of a new evaluation strategy for infarct size measurement using delayed enhancement CMR in comparison to a standard evaluation
Images were thresholded to a level >2 SDs than that of normal myocardium and the infarct was manually traced
Agreement between the experienced and the novel observers was good with -3,0 ± 13,7% for standard evaluation and +3,0 ± 14,1 % for the new evaluation (P=ns)

Summary

Introduction

Cardiac magnetic resonance imaging (CMR) with delayed gadolinium enhancement (DE) enables accurate infarct size measurement, the evaluation of infarct size using a threshold method is time consuming and relies on accurate placement of normal regions of interest and manual delineation of the infarct size.The purpose of the study was to analyze the accuracy and expenditure of time of a new evaluation strategy for infarct size measurement using delayed enhancement CMR in comparison to a standard evaluation.

Objectives

Methods

Results