Abstract

BackgroundDelirium is a frequent and detrimental complication of inpatient hospitalization. Multicomponent intervention in selected groups has been shown to prevent and treat delirium, though little data exists on the effect of intervention in neurological patients. We studied the efficacy of a multicomponent delirium care pathway implemented on a largely neurology and neurosurgery hospital ward among unselected patients.MethodsWe incorporated a multicomponent delirium care pathway into the workflow of a university hospital for patients older than 50 years. The pathway involved risk-stratification for development of delirium, delirium screening, and non-pharmacologic behavioral prevention and intervention. We then retrospectively reviewed admissions before and after implementation of the care pathway. Our primary endpoint was incidence of delirium; secondary endpoints included delirium days, length of stay, restraint use, readmission rates, and discharge disposition.ResultsSeven hundred ninety eight admissions from before the delirium care pathway went into effect and 797 admissions from afterwards were reviewed. Baseline characteristics between groups were similar. Delirium incidence between the two groups did not change (7.0% before vs 7.2% after, p = 0.89). Length of stay among delirious patients significantly decreased after implementation of the delirium care pathway (9.60 before vs 7.06 after, β = − 0.16, adjusted p-value = 0.001).ConclusionImplementation of a delirium care pathway on a neurosciences ward was not associated with changes in the rate of delirium development, though length of stay among delirious patients decreased. In a largely neurologic population, multicomponent intervention to prevent and treat delirium may not change delirium incidence, but may be effective in mitigating delirium complications.

Highlights

  • Delirium is a frequent and detrimental complication of inpatient hospitalization

  • Description of subjects Of 1600 charts chosen for review, 798 admissions were reviewed in the pre-intervention group, and 797 in the after-group

  • There was a significant difference between hospital services in the pre-intervention group compared to the post-intervention group (p = 0.014) among delirious patients only, but otherwise demographic information was similar between epochs

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Summary

Introduction

Delirium is a frequent and detrimental complication of inpatient hospitalization. Multicomponent intervention in selected groups has been shown to prevent and treat delirium, though little data exists on the effect of intervention in neurological patients. Multi-component, non-pharmacologic interventions both prevent the development and mitigate the complications of inpatient delirium [1, 2], but their efficacy has not been studied in neurologic populations. Multi-component interventions implemented by hospital staff have been shown to reduce rates and detrimental outcomes of delirium in many settings [2, 7]. These interventions include frequent reorientation, early mobilization, improvement in sleep regulation, ensuring adequate hydration, treating urinary retention and constipation, and ensuring hearing and visual aids are present if needed [1]. Delirium in neurology and neurosurgery patients may be similar to general medicine

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