Abstract
Objectives: Tissue adhesives (TA) and sealants may offer advantages over sutures during surgery, particularly in the reduction of operative time and procedural simplification, improving patient safety and faster recovery. However, commercially available TA still show limitations such as low adhesive strength and sealing performance, limited control over activation and poor biocompatibility. GB02 is a novel light activated sealant developed by Gecko Biomedical (Paris, France) that aims to fill this unmet clinical need. In this study the performance of GB02 for sutureless closure of vascular incisions is compared with commercially available sealants.
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