Abstract

We have reported that KGSA, representing the hepatic uptake rate calculated from 99mTcGSA liver scintigraphy, is useful to evaluate the liver functional reserve. In this study we tried to predict the liver functional reserve after hepatic resection, setting Matrix ROI on the image of liver scintigraphy. The 99mTcGSA liver scintigraphy combined with Matrix ROI was performed on 17 patients scheduled to be operated on for hepatoceller carcinoma. Five cases of those underwent portal embolization before operation, as well as 99mTcGSA liver scintigraphy immediately before operation, to predict the hepatic functional reserve. After the operation, all cases underwent 99mTcGSA liver scintigraphy, to calculate KGSA and these measurements were compared before and after operation. In 12 cases without portal embolization, we could predict the residual liver function accurately. In 5 cases with portal embolization, we could also predict the residual liver function accurately. From those results we conclude that to predice the residual liver functional reserve using KGSA combined with Matrix ROI before hepatic resection is useful and reliable for safety hepatic surgery.

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