Evaluation of 64-slice spiral digital subtraction CT angiography in the diagnosis of Moyamoya disease

Abstract

Objective To evaluate the diagnostic value of digital subtraction CT angiography (DSCTA) in Moyamoya disease.Methods The cerebral vascular CTA data of 54 patients with Moyamoya disease were analyzed retrospectively. All the original data were processed with non-subtraction and subtraction method.Student t-test was used to compare the post-processing time difference between DSCTA and routine CTA. Chi-square test was used to compare the differences between the detection rates of the stenosis or occlusion in the internal carotid artery (ICA) terminal,the initials of anterior cerebial artery (ACA) and middle cerebral artery (MCA),abnormal vascular network at skull base,and compensatory enlargement of vertebral-basilar artery system.The quality of DSCTA images was also evaluated.Results The quality of DSCTA images could meet the needs of demonstrating intracranial vascular lesions.DSCTA and conventional CTA imaging demonstrated 46 lesions and 32 lesions in ICA terminal,respectively.There was significant difference between the two methods (X~2=9.05 ,P＜ 0.01).Forty-eight ACA initial lesions,52 MCA initial lesions,38 cases with abnormal vascular network at skull base and 17 cases with compensatory enlargement of vertebral-basilar artery system were detected on DSCTA images,while 41,47,34 and 13 cases were detected on conventional CTA,respectively.No difference was found between the two groups (P ＞0.05).The post-processing time was (8.5±2.5)min for DSCTA,which was significantly less than that in conventional CTA [(14.5±2.0) min](t=13.77,P＜0.01).Conclusion DSCTA is a fast,easy and reliable CTA technology,which can improve the demonstration of ICA terminal lesions in patients with Moyamoya disease,and it can be used as a safe and accurate diagnostic method for the diagnosis of Moyamoya disease. Key words: Moyamoya disease ; Tomography; X-ray computed; Angiography; digital subtraction