Abstract
Background: The disorder can be morphological (polycystic ovaries) or predominantly biochemical (hyperandrogenemia). Hyperandrogenism, a clinical hallmark of PCOS, can cause inhibition of follicular development, microcysts in the ovaries, anovulation, and menstrual changes
 Objectives: To study the risk factors for developing metabolic syndrome in PCOS.
 Material and Methods: This is Prospective study, total 100 patients, department of obs and Gynae, women of reproductive agegroup (15-45yrs) attending OPD at Darbhanga medical college and Hospital Laheriasarai, Bihar. Conclusion: This study helps in recognition of this high-risk group and aid in the enforcement of preventive strategies including therapeutic lifestyle modificationsand risk factor management. This will have a promising impact on women’s health and will prevent or delay the outset of varyingcardiometabolic complications in PCOS.
 Keywords: PCOS, metabolic syndrome
Highlights
The aim of our study is to find out the prevalence of metabolic syndrome using the International Diabetes Federation (IDF) criteria in women with Polycystic ovary syndrome (PCOS) reproductive age group so that appropriate life style modifications, pharmacological and non-pharmacological intervention would help in combating and preventing the major deadly cardiovascular disease, stroke etc
Intense research and clinical studies have focused on unravelling the evolution of metabolic syndrome in PCOS
Primary infertility was the presenting complaint in 45 %, secondary infertility in 10 %, hirsutism in 21% and acanthosis in 17%.Prevalence of metabolic syndrome in our study 41%.Age group from 15 to 45 years were included in the study
Summary
To study the risk factors for developing metabolic syndrome in PCOS. Intense research and clinical studies have focused on unravelling the evolution of metabolic syndrome in PCOS. Complex systematic interactions between the various components of metabolic syndrome Insulin resistance and its consequent hyperinsulinaemia, is one of the reason for the pathogenesis of PCOS. Insulin regulates metabolic and mitogenic pathways that function independent of each other[12]. This might explain the paradoxical insulin sensitivity patterns seen in different tissues, for example, resistance in peripheral tissues and retained sensitivity in the ovarian cortex. Metabolic inertia to insulin has been attributed to a International Journal of Medical and Biomedical Studies (IJMBS)
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