Abstract
In this letter, we focus on the relationship between modification bioparticle density (N) and biological regulation ability in extended gate HEMT (EG-HEMT) biosensors. By analyzing, we demonstrate that under the same gate electrodes size (S g) and concentration, N is exponentially related to the area of sensing regions (y) and has fixed exponential magnification −0.65 ± 0.05. This formula had been demonstrated to have perfect universality when testing protein and small molecules. Finally, we apply N to the structural design of EG-HEMT biosensors and projected that 10 y structure has both high biological regulation ability of biosensors and efficient utility of chips.
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