Abstract

Introduction: Intra-arterial drug injection is a rare, but a potentially serious medical emergency. It is most commonly seen as an iatrogenic complication when administering an intravenous medication. Accidental Intra-arterial injection was defined as an intravenous injection administered in the upper limb for any illness, which was followed by sudden severe pain in the limb followed by bluish discoloration of any part of the affected limb. Aim: The aim of the study is to identify the risk factors early on for limb amputation following intra-arterial injection. Also, to assess the efficacy of the various modalities of the treatments administered, and establish a standardized treatment plan for intra-arterial injection to achieve limb salvaging. Materials and methods: A total of twelve cases of accidental intra-arterial injection were studied for the efficacy of early evaluation and management of each. The patients were studied based on Rutherford Classification, clinical history, and Doppler findings. Results: Ten out of the twelve patients presented early and limb salvation was achieved. Conservative treatment and upper limb Fasciotomy proved to aid with the limb salvation. However, two out of the twelve patients presented after 12 hours with complains of blackening of the digits. In these patients, limb salvation was not achieved and Ray’s amputation was performed. All the patients recovered well, with proper functioning of the upper limb. Conclusion: Early evaluation and management of a case of accidental intra-arterial injection is of utmost importance due to its serious complications. Lastly, all medical professionals must be regularly trained in order to prevent such mishaps from happening.

Highlights

  • Intra-arterial drug injection is a rare, but a potentially serious medical emergency

  • Conservative treatment and upper limb Fasciotomy proved to aid with the limb salvation

  • Early evaluation and management of a case of accidental intra-arterial injection is of utmost importance due to its serious complications

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Summary

Introduction

Intra-arterial drug injection is a rare, but a potentially serious medical emergency. It is most commonly seen as an iatrogenic complication when administering an intravenous medication. Accidental intra-arterial injection, whether being self- administered or iatrogenic, is a medical emergency. Diclofenac sodium is a common over the counter drug being used for analgesia It is a non-steroidal antiinflammartory drug (NSAIDs) that is commonly used to treat mild to moderate pain, hyperpyrexia, and inflammation. It is most commonly administered through oral, intramuscular, intravenous, transdermal and rectal routes. Common sites for error are the ante-cubital fossa, groin, and forearm due to the proximity of arteries and the veins at these sites [4]

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