Abstract

Ingestion of a toxic alcohol often occurs when an alcoholic patient cannot obtain ethanol and thus, seeks an ethanol substitute. Methanol produces visual disturbances, while ethylene glycol produces pulmonary and renal disturbances. Ingestion of isopropanol results in acetone production that can lead to central nervous system depression. Unlike methanol and ethylene glycol poisoning, however, isopropanol poisoning generally does not produce major disturbances in acid-base balance. Most clinical laboratories do not perform toxic alcohol analyses. Thus, the clinician relies on interpretation of other clinical laboratory data to ascertain the presence or absence of a toxic alcohol.

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