Abstract
Polycystic ovary syndrome (PCOS) is a significant health problem affecting women during the reproductiveage and characterized by hormonal disturbance resulting in irregular menstrual periods and infertility.Adiponectin is a protein produced by adipocytes and involved in glucose and lipid metabolism. This studyincluded the evaluation of two doses of omega-3 (300 and 600mg/day for 14 weeks). Age, body massindex (BMI), fasting blood glucose level, homeostatic model assessment (HOMA), lipid profile, luteinizinghormone (LH), follicle-stimulating hormone (FSH), prolactin, estrogen and HMW adiponectin levels wereevaluated. Our data showed no significant differences between control group and treatment groups in BMI,age, sex hormones, fasting blood glucose, and HOMA levels. However, the level of HMW adiponectin wassignificantly higher in women treated with 600mg/day for 14 weeks (p < 0.0001) but not 300mg / day ofOmega-3 fatty acids for the same period.
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