Evaluating the Risk Factors and Induced Cardiotoxicity in Breast Cancer Patients

Abstract

Background: Breast cancer (BC) is one of the most common cancers among women. The survival of the BC patients is based on new treatment protocols. Cardiotoxicity is the most common side effect in these patients. Methods: This was a descriptive study in which we selected our patients randomly among the BC patients and used questionnaires for data completion.66 BC patients whose disease were confirmed according to the histology and laboratory data taken to the oncology section of Ahvaz Golestan hospital between 2017 - 2018. Risk factors, history of the patients, and the function of the heart were evaluated 6 and 12 months after chemotherapy through echocardiography. Result: Six months after chemotherapy, the follow-up patients in 6 indicated five significant risk factor included Age (P < 0.03), history of heart disease (P < 0.02), blood pressure (P < 0.00), diabetes (P < 0.00), and cholesterol (P < 0.04), which confirm the dysregulation function of heart and indication of cardiotoxicity. In 12 months follow- up, the result indicated that only the history of heart disease was significantly correlated with cardiotoxicity (P < 0.01). Conclusion: Finally, the detection of risk factors in BC can introduce a prognostic factor when cardiotoxicity occurs simultaneously with the conduction of chemotherapy.