Abstract
Chemoradiation (CRT) side effects in head and neck cancers (HNC) often result in substantial weight loss. Higher body mass index (BMI) is associated with improved recovery from CRT and survival. Emerging evidence suggests that BMI may be used in conjunction with other body composition indices, including skeletal muscle and visceral adipose loss to individualize nutritional assessment and survival prognostication. This study evaluates the effect of body composition changes on survival in a population-based cohort of patients with locally advanced HNC treated with curative intent.
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