Abstract

Drugs can be effective in curing an illness or relieving a symptom but can have harmful side effects. The value of a drug, among others, depends on the trade-off between treatment effectiveness and side effects. There has been a long history that treatment effectiveness and safety are used as two of the most important attributes to determine the value of a drug. This chapter provides an overview of research on evaluating effectiveness and side effects of prescription drugs. We first briefly review the standard industry practice of using clinical trials data to measure the effectiveness and side effects of a drug. We then discuss how researchers may utilize clinical trials to gauge participants’ preferences. After that, we provide a literature review on studying treatment effectiveness and side effects using post-marketing prescription choice data. Lastly, we close the chapter with suggestions on future research questions, for both practitioners and academic researchers.

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