Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 in Wuhan (China). It soon became widespread so that the World Health Organization (WHO) declared the outbreak of COVID-19 as a pandemic crisis. This disease has caused significant morbidity and mortality in the world. Clinical studies reported that there is a significant correlation between genders, immunogenetic variants, serum levels of some circulating factors, blood groups, and different races with severity and mortality of COVID-19 patients. Hence, some studies have investigated the role of individual genetic background in the susceptibility and vulnerability to COVID-19 infection. It is proposed that host genetic polymorphisms affect the onset and progression of COVID-19 infection and could dramatically impact the virus life cycle. This paper aims to review the state-of-the-art research on the roles of genetic variants in host cell membrane proteins and blood circulation factors in the prognosis of patients with COVID-19.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
