Abstract
To investigate the effect of laser bio-modulation irradiation therapy on the scar after surgical correction of unilateral cleft lip. a comparative, open-label study. we conducted the study in a university based tertiary hospital that recruited early wound healers of unilateral cleft lip correction. Eighty patients were divided into two groups: In study's group, patients undergo laser bio-modulation irradiation (n = 60); in the control group, patients were followed-up without intervention (n = 20). In the study's group, patients underwent low-power diode Laser with wavelength of 806 nm and power of 100 mw. The change in the scar of cleft lip patients, which was assessed by clinical examination and ultrasound. The median pigmentation score was significantly lower in the laser group (median = 1; IQR = 1-2) than the control group (median 2; IQR 1-3), with p-value of <0.001. Likewise, the median height score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 1.5; IQR 1.5-2), with p-value of 0.001. The median pliability score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 2.5; IQR 1-3), with p-value of <0.001. Finally, the median vascularity score was significantly lower in the laser group (median = 1; IQR = 1-1) than the control group (median 1.5; IQR 1-2), with p-value of <0.001. laser bio-modulation irradiation therapy demonstrates a potential efficacy in managing the hypertrophic scars after surgical repair of unilateral cleft lip.
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