Evaluating the distribution of A 12 LDL-C raising variants score in patients with familial hypercholesterolemia

E Olmastroni,M Gazzotti,M Arca,M Averna,M Casula,A.L Catapano

doi:10.1016/j.atherosclerosis.2021.06.543

Evaluating the distribution of A 12 LDL-C raising variants score in patients with familial hypercholesterolemia

E Olmastroni, M Gazzotti + Show 4 more

https://doi.org/10.1016/j.atherosclerosis.2021.06.543

Copy DOI

Journal: Atherosclerosis

Publication Date: Aug 1, 2021

Affiliation: University of Milan, Policlinico Umberto I, Sapienza University of Rome

#Familial Hypercholesterolemia #Polygenic Cause + Show 6 more

Abstract
Full-Text
Similar Papers

Abstract

Background and Aims: A significant proportion of individuals clinically diagnosed with familial hypercholesterolemia (FH) but without a disease-causing mutation are likely to have a polygenic cause for their hypercholesterolemia. This study aimed at evaluating the distribution of a polygenic risk score, comprised of 12 LDL cholesterol (LDL-C) raising variants (LDLc-score), in subjects clinically diagnosed with FH.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title

Journal

Date

Author

More From: Atherosclerosis

Paper Title

Journal

Date

Author

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.