Abstract
Objective: Assessing the clinical application value of Ferric Citrate Effervescent granules (FAC) in magnetic resonance cholangio-pancreatography (MRCP) inspection. Methods: We invited 10 patients who were diagnosed with diseases of the pancreas system and bile duct system and undergoing magnetic resonance cholangio-pancreatography and use Ferric Citrate Effervescent granules in the MRCP process. The time of their MRCP is from May 2018 to February 2020. In addition, we collected the information from the participants, that the information included Sequence and scanning parameters of Mr Cholangiopancreatography, Image quality score before and after MRCP administration, contrast to noise ratio (CNR) score and comparison score of different parts in MRCP images before and after drug administration. Result: In scanning parameters, the data is standard in research, that the TR and TE of 2d MRCP and 3D MRCP are similar, that are > 6000 and > 500. But Layer thickness/Layer spacing between the objects had big gap in data, that are 50/0 and 1.8/0. Additionally, FOV had little different length, which is 40 vs 36. In NEX, they are same. In image quality score, it has higher score after taking the FAC. The CNR score research is similar, that FAC affect the CNR outcome. Conclusion: the FAC provide the improvement to the outcome of patient in MRCP process, that it improves image quality of MRCP.
Highlights
In medical imaging, the magnetic resonance cholangio-pancreatography (MRCP) is common detection method
We invited 10 patients who were diagnosed with diseases of the pancreas system and bile duct system and undergoing magnetic resonance cholangio-pancreatography and use Ferric Citrate Effervescent granules in the MRCP process
We collected the information from the participants, that the information included Sequence and scanning parameters of Mr Cholangiopancreatography, Image quality score before and after MRCP administration, contrast to noise ratio (CNR) score and comparison score of different parts in MRCP images before and after drug administration
Summary
The magnetic resonance cholangio-pancreatography (MRCP) is common detection method. As the development of science and technology in medical electronics, the quality of the MRCP images was improved by many three-dimensional (3D) sequences. In 3D MRCP, it uses a maximum intensity projection or volume rendered technique for accurate display of the biliary tree and pancreatic duct [4,5,6]. As the adoption of heavy T2 weighted MRCP imaging, images of gastrointestinal fluid often overlap with the pancreatic bile duct when doctor use MRCP to test the patient. During MRCP examination, simultaneous development of gastric and intestinal fluids showed high signals, which interfered with the display of biliary and pancreatic ducts. In Chinese hospital, the doctor often uses ferric ammonium citrate granules (FAC) to improve image quality of MRCP [15, 17]
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