Evaluating of some heart and liver enzymes in patients with myocardial infarction in Wasit.

Abstract

The aim of the study was to evaluate some heart and liver enzymes in patients with myocardial infarction in Wasit . Myocardial infarction (MI) is a major cause of death and disability worldwideA heart attack, also known as myocardial infarction, occurs when blood flow to a section of the heart is cut off, resulting in the death of heart cells. This usually happens when a coronary artery becomes blocked due to the rupture of a vulnerable plaque made up of cholesterol, fatty acids, and white blood cells. The study took place in the cardiac resuscitation unit at Al-Zahra Teaching Hospital and Al-Karama Teaching Hospital in Wasit Governorate from November 2022 to January 2023. Its objective was to examine the significance of physiological, immunological indicators, and inflammatory biomarkers for accurately diagnosing, assessing risk, and predicting the future outcomes of patients with acute myocardial infarction. The study included 100 patients with acute myocardial infarction, including 71 men aged30-70 years, and 29 women aged 33-75 years. And 50 samples from the control, 28 samples from men and 22 samples from women, and they were divided into three age groups. The first group is 30-45 years old, the second group is 46-60 years old, and the third group is 61-75 years old. Taking into account the risk factors for acute myocardial infarction, which include Sex, age, high blood pressure, diabetes, smoking, and dyslexia. Lipid lipids through a questionnaire. The results of our study with regard to the diagnostic signs of myocardial infarction revealed a significant increase in troponin, myoglobin, and H-FABP, and a significant decrease in Creatine kinase. This study also indicated, regarding the results of liver enzymes, a significant increase in both AST and ALT at p≤ 0.5. Conclusions: In patients with AMI, The plasma level of significant increase in troponin, myoglobin, and H-FABP, and a significant decrease in Creatine kinase AST and ALT at p≤ 0.5.