Abstract
Material and methods 97 AIS girls and 99 female controls between 11-14 years old were recruited. Dietary calcium intake and physical activity level were assessed with a standard Food Frequency Questionnaire and the Modified Baecke Questionnaire respectively. With HR-pQCT, an established model on morphology and micro-structure of the nondominant distal radius was generated for FEA in terms of Stiffness, Failure Load and Apparent Modulus. Multivariate linear regression analysis was used to investigate the difference between AIS and controls after adjusting for age in Model 1 and for age, calcium intake and physical activity level in Model 2.
Highlights
The objective of this study is to evaluate bone mechanical properties with finite element analysis (FEA) using in-vivo High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) in Adolescent Idiopathic Scoliosis (AIS) and compare that with normal controls
This indicated the presence of an underlying biochemical or biomechanical mechanism yet to be identified that could be responsible
Summary
Evaluating bone strength with finite element analysis for Adolescent Idiopathic Scoliosis (AIS): a case-control study with HR-pQCT. Ka Yee Cheuk1*, Tsz Ping Lam[1,2], Lyn Lee Ning Wong[1], Alec Lik Hang Hung[1], Arthur Fuk Tat Mak[3], Kwong Man Lee[4], Bobby Kin Wah Ng1,2, Jack Chun Yiu Cheng[1,2]. From The 10th Meeting of the International Research Society of Spinal Deformities (IRSSD 2014 Sapporo) Sapporo, Japan. From The 10th Meeting of the International Research Society of Spinal Deformities (IRSSD 2014 Sapporo) Sapporo, Japan. 29 June - 2 July 2014
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