Abstract

Streptococcus thermophilus have potent antimicrobial activities toward closely related bacteria and undesirable harmful microorganisms. Certain S. thermophilus strains are able to produce substances that compete and prevent pathogenic bacteria from adhering to the receptors on epithelial cells of intestinal surfaces. The potential probiotic effects ofS. thermophilus are well known in the human ecosystem and their production of antimicrobial peptides can contribute to elucidate the precise mechanisms by which S. thermophilus can dominate the intestinal microbiota and achieve their probiotic function. This paper presents a review of the antimicrobial proteinaceous compounds produced by various streptococcus strains, the attempts made to purify them, their characterization and useful applications. Key words: Streptococcus thermophilus, bacteriocin.

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