Abstract

Aim & Objectives: To evaluate the analgesic activity of Tukhme Karafs (Apium graveolens seed) in Albino mice. Methods: The analgesic activity was determined by Hot plate method, Tail immersion method, Tail Clip method and Writhing test. Result: Petroleum ether extract of seeds of Apium graveolens (PEESAG) was tested in adult Albino Swiss mice weighing 20-30gms, at the dose of 50, 75, and 100 mg/kg body weight by different method i.e. hot plate method, tail immersion method, tail clip method and Wrihting method. The result show mild to moderate analgesic activity of celery seeds. Conclusion: The petroleum ether extract of celery seeds revealed mild to moderate analgesic activity.

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