EVALUATE PRELIMINARY RESULTS OF SURGERY FOR GASTRIC CANCER COMBINATED ADJUVANT CHEMOTHERAPY

Abstract

Purpose: To review some characteristics of patients and evaluate preliminary results of adjuvant chemotherapy for patients with resected gastric cancer. Objectives and Methods:The study was conducted on 30 patients with gastric cancer (male/female = 20/10) treated by adjuvant chemotherapy after gastrectomy at the Digestive Surgical Depatment at Hue Central Hospital from January. 2011 to May. 2012. We noted their clinical and paraclinical signs and studied the preliminary results of adjuvant chemotherapy after gastrectomy for gastric cancer. Results: The male/female = 2/1, The common group of age is 41-60, accounting for 63,33%. The primary tumor were found mostly at antrum and pylorus (66,67%).The postoperative mortality and morbidity common rates were 0% and 3,33%. Almost patients treated by adjuvant chemotherapy from 4-8 weeks after gastrectomy (73,33%). Fatigue is the most common toxicity of chemotherapy with 33,33% and alopecia was 26,67%. The follow-up time is about 11 months (rank 6-15 months). The life time expectancy of all 30 patients by stages disease: Stage II: 100%, stage III: 94,17% and stage IV: 16,67%. Conclusion: We review general characteristics of patients, and evaluate the results of surgery, quality of life after surgery combine with supportive care. Number of patients with total points within the 8-10 points by Spitzer index from 70% to 80% after the second re-examination. Most of chemotherapy toxicity is tolerable. However, this study needs to be carry out in the longer time, with larger number of patients. Key words: gastric cancer, chemotherapy