Abstract

Background: End Stage Renal Disease (ESRD) occurs when Glomerular Filtration Rate (GFR) falls below 15 ml/minute/1.73m2. This condition leads to Renal Replacement Therapy (RRT) intervention namely dialysis and kidney transplantation. The intervention inclines morbidity and hospitalization rate which means more physical and financial burden to patients as the consequences. One of the physical side effects that becomes a major cause of increasing cardiovasculer mortality is hypertension.
 Objective: The purpose of this study was to analyze the rationale of antihypertensive therapy in haemodialysis patients.
 Methods: A descriptive, purposive, non experimental study gathering medical records of 97 hemodialysis with antihypertensive therapy patients of PKU Muhammadiyah Gamping hospital who were admitted from June until August 2018 was held in this study.
 Results: Majority of patients were female (63,92%), aged between 41-75 years (83,50%), and diagnosed with chronic kidney disease (CKD) (95,58%), received three combination of antihypertensive drugs (38,14%) using Calcium Channel Blocker namely amlodipin (20,86%). The analysis of antihypertensive therapy including accurate drugs, patients, and dosage were 83,51%, 100%, and 97,72% respectively.
 Conclusion: The use of antihypertensive drugs in CKD patient in PKU Muhammadiyah Gamping was approprite
 Keywords: Antihypertension, chronic kidney disease, evaluation, hemodialysis, hospital.

Highlights

  • End Stage Renal Disease (ESRD) occurs when Glomerular Filtration Rate (GFR) falls below 15 ml/minute/1.73m2

  • This condition leads to Renal Replacement Therapy

  • of the physical side effects that becomes a major cause of increasing cardiovasculer mortality is hypertension

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Summary

Diabetes Melitus

Berdasarkan tabel 1 jumlah pasien laki-laki penderita hipertensi dengan hemodialisis lebih banyak dengan jumlah 62 orang (63,92%) dibandingkan dengan pasien perempuan dengan jumlah 35 orang (36,46%). Hal ini sesuai dengan penelitian yang menyebutkan bahwa persentase jenis kelamin pasien hemodialisis pada laki-laki sebesar 74% dan 52,8%.5. Usia pasien penderita hemodialisis terbanyak pada rentang usia 41-75 tahun (83,50%). Hal ini dikarenakan semakin bertambahnya usia maka fungsi organ tubuh akan semakin menurun sehingga fungsi pembuluh darah dan ginjal akan semakin kehilangan keelastisannya dalam memodulasi tekanan darah. Diagnosa dan riwayat penyakit pasien menurut data hasil adalah gagal ginjal kronik, gagal ginjal kronik dan hipertensi, gagal ginjal kronik dan diabetes melitus, gagal ginjal kronik, hipertensi, dan diabetes melitus, serta gagal ginjal kronik, hipertensi, diabetes melitus, dan penumonia

Agen antihipertensi yang digunakan sesuai dengan pedoman Joint National
Vasodila tor
Isosorbid Dinitrat
Universitas Jenderal Achmad Yani
Full Text
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