Abstract
Arterial stiffness provides an indirect picture of vascular calcifications in terms of the effect they have on the systemic circulation and consequently on the heart. The present study sought to demonstrate the usefulness of outpatient investigation of vascular calcifications in dialysis patients using pulse wave velocity (PWV) determination. The aim of the study was to determine arterial resistance in patients with chronic dialysis kidney disease. The average study period was 48.5 ± 19.0 (SD) months. The study included 203 patients on dialysis with BCRT. The determination of arterial stiffness was measured at an interval of one hour after the dialysis session. The study highlighted the presence of an increased cardiovascular risk related to the presence of vascular calcifications without being able to establish a direct linear and causal link between their presence, location and the risk of cardiovascular events. The importance of highlighting calcifications and the consequences they generate means the possibility of influencing the main elements that can generate acute cardiovascular events. The results obtained and the correlations performed give an overview of the pathology studied, providing premises for therapeutic influence and risk assessment.
Highlights
Arterial stiffness provides an indirect picture of vascular calcifications in terms of the effect they have on the systemic circulation and on the heart
Valoarea suprafeţei corporale şi a IMC a fost calculată pe baza softurilor acreditate dependent de înălţime şi greutatea uscată
Parametrii oferiţi de arteriograf sunt: tensiunea sistolică centrală, presiunea pulsului centrală, viteza de propagare a undei de puls din aortă pulse wave velocity (PWV), deviaţia standard a PWV Ao, indice de augmentare brahial AIX br, indice de augmentare aortică AIX AO, timp de reflecție a undei de puls în aortă RT S35, frecvenţa cardiacă, presiunea undei de puls PP, indice masă corporală BMI
Summary
Scopul studiul a constat în determinarea rigidității vasculare secundare calcificărilor vasculare la pacienţii dializaţi ambulator şi corelarea datelor obţinute cu factorii de risc convenţionali şi specifici, precum şi impactul pe care calcificările vasculare îl au asupra disfuncţiei aparatului cardiovascular, cu implicaţii asupra morbidităţii şi mortalităţii
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