Evaluación de los criterios de clasificación SLICC en pacientes con lupus eritematoso sistémico juvenil seguidos en una clínica pediátrica de Bogotá, Colombia

Abstract

IntroductionSystemic lupus erythematosus is a multisystemic disease that is associated with an increase in morbidity. Several classification criteria, with a variable performance, have been published in the last few years. The Systemic Lupus International Collaborating Clinics (SLICC) recently developed a new version that has been validated in children and adults. The performance of these criteria in Colombian juvenile lupus patients is unknown. ObjectivesTo evaluate the sensitivity and specificity of the SLICC criteria in a group of patients with juvenile systemic lupus erythematosus in Bogotá, Colombia. Materials and methodsRetrospective evaluation of clinical and laboratory data during the first month of disease in patients with juvenile systemic lupus erythematosus and in control patients followed-up in a paediatric rheumatology clinic. ResultsThe study subjects (n=110), with a mean age of 11.1 years (2-16 years), were divided equally into cases and controls. The gender ratio in cases was F:M 5.4:1 and in controls 1.8:1. The ACR 1997 and SLICC criteria were analysed in both groups of patients. The sensitivity and specificity of ACR criteria were 78% and 96%, respectively, and in SLICC criteria were 89% and 87%, respectively. ConclusionsIn this group of paediatric patients, the sensitivity of SLICC criteria during the first month of diagnosis was higher than the ACR 1997 criteria. This was associated with a lower specificity. These results are similar to those of previous studies.