Abstract
The infiltrative ophthalmopathy of Graves's disease may precede, accompany or follow the onset of hyperthyroidism. Proptosis, soft-tissue involvement and ophthalmoplegia, occurring in an obviously thyrotoxic patient, or in one with a history of hyperthyroidism, pose no problem, but diagnosis is more difficult when such changes occur in apparently euthyroid persons since not only euthyroid Graves's disease (also termed Graves's ophthalmopathy and endocrine exophthalmos) but primary orbital disorders must then be considered. Werner's observation, 20 years ago,1 that in nine out of 10 cases of euthyroid Graves's disease, uptake of radioiodine by the thyroid gland was not normally suppressed by administered . . .
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